The quinoline ring systems are important structural units in naturally occurring alkaloids and synthetic analogues with interesting biological activities. In this paper, we propose the synthesis of 2-(4-Methoxy-phenyl)-6, 7, 8, 9 - tetrahydro-2H-11-oxa- 2, 4, 10-triaza -benzo[b]fluoren-1-one. Therefore, the development of new and efficient synthetic route for the preparation of their analogues is of importance in both synthetic organic chemistry and medicinal chemistry.

Key words: Methylation, Synthetic Compound, anti-diabetic, quinoline, DMF, anti-diabetic